Recent developments in genomic science hold out the tantalizing prospect of soon being able to treat and prevent a wide variety of medical conditions through gene therapy. In time, it may be possible to use similar techniques not simply to combat disease but also to enhance, or improve on, normal human functioning.

This chapter aims to show that prospective parents are not bound in their reproductive decision making by a principle of procreative beneficence. That is, they have no obligation (as Julian Savulescu, the principle’s originator, famously thinks they have) to choose the possible child, from a range of possible children they might have, who is likely to lead the best life. I will summarise and clarify the content of previous papers of mine, in which I argue that since the sorts of (...) considerations that underlie the principle of procreative beneficence do not constitute reasons when viewed from a perspective that it is fitting and appropriate for a prospective parent to take up, there can be no requirement for prospective parents to be moved by those considerations. (shrink)

In recent decades, scientists have begun to identify the brain processes and neurochemicals associated with the different stages of love, including the all-important stage of attachment. Experimental findings—readily seized upon by those bioethicists who want to urge that we sometimes have good reason pharmaceutically to enhance flagging relationships—are presented as demonstrating that attachment is regulated and strengthened by the neuropeptides oxytocin and vasopressin. I shall argue, however, that often what the experimental data in fact show is only that exogenous administration (...) of such chemicals can control and intensify the trappings of attachment, not attachment itself. That this is sometimes overlooked by both scientists and ethicists, is due to attachment being miscategorised as a set of feelings or a drive, rather than as a disposition to think about, feel toward, and behave toward its object in certain distinctive ways. (shrink)

Recent developments in genomic science hold out the tantalizing prospect of soon being able to treat and prevent a wide variety of medical conditions through gene therapy. In time, it may be possible to use similar techniques not simply to combat disease but also to enhance, or improve on, normal human functioning.

Recent developments in genomic science hold out the tantalizing prospect of soon being able to treat and prevent a wide variety of medical conditions through gene therapy. In time, it may be possible to use similar techniques not simply to combat disease but also to enhance, or improve on, normal human functioning.

Tom Beauchamp and James Childress have always maintained that their four principles approach (otherwise known as principlism) is a globally applicable framework for biomedical ethics. This claim is grounded in their belief that the principles of respect for autonomy, non-maleficence, beneficence and justice form part of a 'common morality', or collection of very general norms to which everyone who is committed to morality subscribes. The difficulty, however, has always been how to demonstrate, at least in the absence of a full-blooded (...) analysis of the concept of morality, whether the four principles are foundational, and so globally applicable, in this way. In the recently published sixth edition of Principles of Biomedical Ethics, an imaginative and non-question-begging empirical method of determining the common morality's norms is suggested. In this paper, I outline this method, before arguing that it is difficult to see how it might be thought to achieve its purpose. (shrink)

Sober (1992) has recently evaluated Brandon's (1982, 1990; see also 1985, 1988) use of Salmon's (1971) concept of screening-off in the philosophy of biology. He critiques three particular issues, each of which will be considered in this discussion.

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

Friendships have important influences on children's well-being and future adjustment, and interpersonal forgiveness has been suggested as a crucial means for children to maintain friendships. However, existing measures of preadolescent children's forgiveness are restricted by developmental limitations to reporting emotional responses via questionnaire and inconsistent interpretations of the term “forgive.” This paper describes development and testing of concurrent and discriminant validity of a pictorial measure of children's emotional forgiveness, the Children's Forgiveness Card Set. In Study 1, 148 Australian children aged (...) 8–13 years responded to a hypothetical transgression in which apology was manipulated and completed the CFCS and extant measures of forgiveness and socially desirable responding. Following an exploratory factor analysis to clarify the structure of the CFCS, the CFCS correlated moderately with other forgiveness measures and did not correlate with socially desirable responding. Apology predicted CFCS responding among older children. In Study 2 an exploratory factor analysis broadly replicated the structure of the CFCS among a sample of N = 198 North American children aged 5–14 years. We also fitted an exploratory bi-factor model to the Study 2 data which clarified which cards best measured general forgiveness, or positive or hostile aspects of responding to transgressions. Apology once again predicted the CFCS, this time regardless of age. The CFCS appears a potentially valid measure of children's emotional forgiveness. Potential applications and differences between explicit and latent forgiveness in children are discussed. (shrink)

then essentially characterized the hypotheses that mechanical scientists can successfully decide in the limit in terms of arithmetic complexity. These ideas were developed still further by Peter Kugel [4]. In this paper, I extend this approach to obtain characterizations of identification in the limit, identification with bounded mind-changes, and identification in the short run, both for computers and for ideal agents with unbounded computational abilities. The characterization of identification with n mind-changes entails, as a corollary, an exact arithmetic characterization (...) of Putnam's n-trial predicates, which closes a gap of a factor of two in Putnam's original characterization [12]. (shrink)

Marc Alspector-Kelly claims that Bas van Fraassen’s primary challenge to the scientific realist is for the realist to find a way to justify the use of some mode of inference that takes him from the world of observables to knowledge of the world of unobservables without thereby abandoning empiricism. It is argued that any effort to justify such an “inferential wand” must appeal either to synthetic a priori or synthetic a posteriori knowledge. This disjunction turns into a dilemma for (...) the empirically-minded realist as either disjunct leads to unwanted consequences. In this paper, I split the horns of this dilemma by arguing that the realist can justify one particular such mode of inference – abduction – without committing himself to rationalism. The realist may justify this mode of inference by appealing to the analytic a priori axioms of the probability calculus. I show that Peter Lipton’s tripartite defense of abduction constitutes such a method of justification. (shrink)

An experimenting society is one in which policy-relevant knowledge is created. It is then critically assessed and communicated in real-life or natural settings, with the aim of discovering new forms of public action to improve the problem-solving capacities of society. This latest volume of the distinguished Policy Studies Review Annual series probes, evaluates, and augments the work of Donald T. Campbell on an experimental societies. A basic assumption of this volume is that Campbell's perspective supplies a useful way to address (...) increasingly complex and seemingly unmanageable problems facing the United States and other postindustrial societies. This volume is also the fourteenth festschrift to be issued by Transaction. The focus is on theoretical as well as practical options for creating an experimenting society. The rationale for this focus is the belief, increasingly -shared in the social science and policy-making communities alike, that researchers are essentially ignorant about how to solve many of the most pressing larger problems of this epoch. This frank recognition of ignorance is a prerequisite of genuine scientific and professional curiosity, without which knowledge gains are next to impossible to achieve, and a'precondition of an experimenting society. Contributors to this original volume include: Steve-Fuller, Duncan MacRae, Jr., Anthony S. Bryk, Robert A. Beauregard, Rita Mae Kelly, Peter Gregware, Burkart Holzner, B. Guy Peters, C. West Churchman, and Ian I. Mitroff. Their multidisciplinary competencies are at once philosophical, methodological, and substantive. They address such questions as: What new or bold policies are available in domains such as education, science, and urban development? In what ways can theoretical knowledge and practical action be fused so as to illuminate or alleviate policy problems? What should be done? Included are excerpts from Campbell's foundational paper "The Experimenting Society," as well as a recent article entitled "Methods for the Experimenting Society," which circulated in unpublished form for many years. An unusual feature of the book is Campbell's responses to those who have addressed his work with candor and intelligence. It will be of interest to policy studies scholars, sociologists, and social scientists. (shrink)

Jesus of Nazareth, like Socrates, left nothing behind written by himself. Yet, the records of his teaching indicate a rich interest in dialogic pedagogy, reflected in his use of the parable, primarily an oral genre, as a dialogic provocation. Working at the interface of pedagogy, theology and philosophy, this article explores the parable of the Good Samaritan from the perspective of dialogic pedagogy. It employs an analytical approach termed diacognition, developed from the notions of dialogue, position and cognition, to analyse (...) the moves within the parable and the teaching situation in which it is located. The article explores how Jesus engages the dialogue of and around the parable to position and reposition his interlocutor, provoking a re-cognition of what it means to love one’s neighbour. It concludes by reflecting on the implications of this analysis for the relation of meaning to knowing and doing. (shrink)

Happiness in World History traces ideas and experiences of happiness from early stages in human history, to the maturation of agricultural societies and their religious and philosophical systems, to the changes and diversities in the approach to happiness in the modern societies that began to emerge in the 18th century. In this thorough overview, Peter N. Stearns explores the interaction between psychological and historical findings about happiness, the relationship between ideas and popular experience, and the opportunity to use historical (...) analysis to assess strengths and weaknesses of dominant contemporary notions of happiness. Starting with the advent of agriculture, the book assesses major transitions in history for patterns in happiness, including the impact of the great religions, the unprecedented Enlightenment interest in secular happiness and cheerfulness, and industrialization and imperialism. The final, contemporary section covers fascist and communist efforts to define alternatives to Western ideas of happiness, the increasing connections with consumerism, and growing global interests in defining and promoting well-being. Touching on the experiences in the major regions of Asia, Africa, Latin America, Europe, and North America, the text offers an expansive introduction to a new field of study. This book will be of interest to students of world history and the history of emotions. (shrink)

American parents greatly value children’s happiness, citing it well above other possible priorities. This commitment to happiness, shared with parents in other Western societies but not elsewhere, is an important feature of popular emotional culture. But the commitment is also the product of modern history, emerging clearly only in the 19th century. This article explains the contrast between more traditional and modern views, and explains the origins but also the evolution of the idea of a happy childhood. Early outcomes, for (...) example, included the novel practice of hosting parties for children’s birthdays, another mid-19th-century innovation that has expanded over time. Explaining the intensification of the happiness commitment also reveals some of the downsides of this aspect of popular emotional culture, for example in measurably complicating reactions to childish unhappiness. The basic goal of the essay is to use this important facet of modern emotional history to evaluate a commitment that many modern parents assume is simply natural. (shrink)

The present paper tries to trace the particular contours that the problem of theodicy assumes in the Chinese Buddhist text the Awakening of Faith in the Great Vehicle. It analyses the beginning section of the main body of text – the section, that is, that outlines the major theoretical structure of the work – in terms of a problem that has been of particular concern in western theology. I believe that taking such a tack is especially valuable for highlighting the (...) central Problematik around which the text is organized. The paper will thus use the problem of theodicy as a means of exploring some of the philosophical implications of the Awakening of Faith. (shrink)

This article argues that community-based research (CBR)—research that includes the participation of “lay” citizens in the research process—is changing the process of research and knowledge production. The article is an initial attempt to examine the outcomes of CBR and the impact such research is having on knowledge development and funding trends in North America. The article concludes with a set of policy recommendations and areas for further research.

Nicolas-Claude Fabri de Peiresc was een geleerde die niet tot een bepaalde institutie hoorde. Hij streefde naar de vooruitgang van wetenschappelijke kennis, had een netwerk van geleerden, politici, kooplieden en anderen en had contacten in Goa en Ethiopië, in het Ottomaanse Rijk en in christelijk Europa. Hij bewoog zich onder meer op terreinen als astronomie en de kennis van bijbelhandschriften in oosterse talen en werkte samen met protestanten, joden en moslims. Gedachte-experiment: iemand als Peiresc die internet ter beschikking heeft. Peiresc (...) heeft geen publicaties nagelaten en postuum hebben zijn vrienden zijn brieven niet gepubliceerd. Maar de archiefnalatenschap van deze briljante spin in zijn web is in onze tijd beschikbaar. (shrink)

Prompted by the concerns about legitimacy that Josh Reeves expresses in his book Against Methodology in Science and Religion: Recent Debates on Rationality and Theology, this article considers how the field of science and religion, and the disciplines and scholars that comprise it, should think about the pursuit of legitimacy today. It begins by examining four features of any conferral of legitimacy on an object. It then looks more closely at distance and its effects on judgments of legitimacy. It first (...) notes how longer distances can enable a wide range of factors other than the internal features or inherent merits of the object to influence judgments of its legitimacy. It then explores the factors that persons who have significant expertise in or experience with the object may consider when judging its legitimacy. It closes by posing three questions that anyone designing a strategy to increase the perceived legitimacy of an object might ask. (shrink)

A novel photon-based proton model is developed. A proton’s ground state is assumed to be coherent to the degree that all of its mass-energy precipitates into a single uncharged spherical structure. A quantum vortex, initiated by the strong force, but sustained in the proton’s ground state by the circular Unruh effect and a spherical Rindler horizon, is proposed to confine the proton’s mass-energy in its ground state. A direct connection between the circular Unruh effect, the zitterbewegung effect, spin, and general (...) relativity is proposed. Such a structure acts as an uncharged zitterbewegung fermion, and may explain neutrino mass. A ground-state proton’s central zitterbewegung fermion is assumed to be surrounded by a halo of charge shells of both signs. Virtual photon standing waves are assumed to synchronize the inner shell with the central zitterbewegung fermion. The charge shells are proposed to be associated with isospin and proton g-factor. There are only two model inputs—proton mass and quantized electronic charge—and just one adjustable parameter. The adjustable parameter, reduced only by about 0.4% from an initial estimate, provides the proton’s experimentally determined magnetic moment to arbitrary precision. The resulting modeled proton charge radius agrees very well with the 2018 CODATA value. Magnetic moment and charge radius are calculated algebraically in a manner easily understood by undergraduate physics students. This proposed ground-state proton model could be considered a low-energy approximation to a full quantum chromodynamical proton model. (shrink)

This article uses historical analysis of shame to argue for a more active connection between emotions history and the other disciplines that deal with emotion. It assesses the current state of historical work on shame, including the argument for a 19th-century decline; it juxtaposes current social psychological and anthropological work with this argument. Additional data allow more precise consideration of changing patterns of shame, reasons for change, and probable impacts including increasing complexity in individual and social reactions alike. Evaluation includes (...) the unexpected increase in shame discussions in recent decades; the possibility that shame and “modernity” are ultimately incompatible; and some larger problems attached to the decline of shame. (shrink)

This article focuses on the rise of world history and the challenges it poses to curricula that emphasize history in service to national or civilizational identity. The nature and causes of the world history movement are juxtaposed to the continuing or renewed attachment to more nationalist history. Specific clashes around world history, particularly but not exclusively in the United States, have focused on opposing views about history and identity. Compromises continue to results, as well as clear delays in world history (...) interest in many regions and many programs. Yet world history continues to gain ground, fundamentally because, at its best, it provides many of the tools needed for responsible understanding of globalization past and present. (shrink)

The theme of this book is the crisis of the early modern state in eighteenth-century Britain. The revolt of the North American colonies and the simultaneous demand for wider religious toleration at home challenged the principles of sovereignty and obligation that underpinned arguments about the character of the state. These were expressed in terms of the 'common good', 'necessity', and 'community' - concepts that came to the fore in early modern European political thought and which gave expression to the problem (...) of defining legitimate authority in a period of increasing consciousness of state power. The Americans and their British supporters argued that individuals ought to determine the common good of the community. A new theory of representation and freedom of thought defines the cutting edge of this revolutionary redefinition of the basic relationship between individual and community. (shrink)

Among the newly enchristianed "extreme sports" category, ultrarunners and the sport of ultrarunning is on the fringe edge. What makes ultrarunners and their "sport" interesting is that ultrarunners regularly report experiences that can be equated to various types of mystical experiences during their "sporting" events. This paper briefly discusses ultrarunners, a hypothetical mystical (mythical) state of consciousness called Absolute Unitary Being, and the psychoneurophysiological aspects of ultrarunning. Through this process, a link is established that connects ultrarunners and their "sport" with (...) many traditional indigenous practices. It is suggested that many of the traditional indigenous practices may have produced experiences similar to those of ultrarunners, and thus we can look to ultrarunners to begin to understand some of the physiological, psychological, neurological, as well as humanistic, phenomenological, and transpersonal experiences and reasons behind many now lost traditional indigenous practices. (shrink)

Hai, Peter NV Lay people have always played a vital role in the life and mission of the church but it is only after the Second Vatican Council that the question of the laity has come into focus in a new way in Catholic theological reflection. Indeed, in the wake of Vatican II, the council that introduced a Copernican shift in the Catholic understanding of the laity, lay people have become the theme of a Synod of Bishops, the subject (...) of an Apostolic Exhortation, and the topic of several pastoral statements of national conferences of bishops. This paper begins with a review of the state of the question highlighting the need for a comparative investigation of the theologies of the laity according to John Paul II, the Federation of Asian Bishops' Conferences, and the Vietnamese Episcopal Conference. It then highlights the differences and convergences in these theologies. As all three theologies draw their inspiration from the teachings of Vatican II, and a prominent element of the council's concerns was the emphasis on the universal call to holiness, we will also provide a detailed comparison of this notable aspect across these theological systems. Our argument is that while some minor points of divergence and disagreement remain there is a greater convergence and agreement between these theologies of the laity. (shrink)

Identifying corporate governance mechanisms to improve firm performance has been at the forefront of policy discussion and research in recent years. Existing research in this area focuses on large-capitalisation firms, and has not provided much insight on smaller firms. This paper tests for the optimality of deployment of governance mechanisms for Canadian small-cap firms by estimating a simultaneous equation system that links four control mechanisms to firm performance, using recent data. The results confirm simultaneity between several governance mechanisms and Canadian (...) small-cap firm performance. CEO ownership and shareholder rights are shown to determine board independence. CEO ownership in turn is shown to depend on the extent of shareholder rights and whether the CEO is also Chairperson of the board. Canadian small-cap firms appear to overutilise debt as a control mechanism. There is somewhat weaker evidence that board independence and CEO ownership are beyond the optimum. The latter, given the relatively high degree of CEO ownership in Canadian small-cap firms, is consistent with management entrenchment. We also do not find any significant discount to performance for Quebec-based firms, or for firms with dual or multiple voting class shares structures. (shrink)

The need for more comparative analyses in emotions research is increasingly obvious. Recent discussions of fear raise clear issues of “national” patterns and expressions versus standard societal or at least modern responses, and only explicit comparison can clarify. The same applies to current impacts on emotions from contemporary media or broader processes of globalization. Happily, there are some good examples of comparison to build upon, though the challenges of dealing with the complexity of different cultures, and potential causes of differences (...) remain very real. The agenda and the potential for additional understanding of emotional experience through comparison are rich and stimulating. (shrink)

Introduction : what and why is world history? -- A world history skeleton -- Habits of mind in world history -- Managing time : choosing and evaluating world history periods -- Managing space : world history regions and civilizations -- Contacts and the structure of world history -- Topics in world history -- Disputes in world history -- World history in the contemporary era.

Looks at how history affects contemporary life, discusses the individual's role in history, and describes the author's efforts to popularize history.

In lieu of an abstract, here is a brief excerpt of the content:Citizenship and Culture in Early Modern EuropePeter N. MillerCharlotte Wells, Law and Citizenship in Early Modern France (Baltimore: The Johns Hopkins University Press, 1995), xviii, 198p.Paula Findlen, Possessing Nature: Museums, Collecting, and Scientific Culture in Early Modern Italy (Berkeley, Los Angeles, and London: University of California Press, 1994), xviii, 449p.Steven Shapin, The Social History of Truth: Civility and Science in Seventeenth-Century England (Chicago and London: University of Chicago Press, (...) 1994), xxiv, 483p.Anne Goldgar, Impolite Learning: Conduct and Community in the Republic of Letters 1680–1775 (New Haven and London: Yale University Press, 1995), xv, 395p.Lawrence Klein, Shaftesbury and the Culture of Politeness: Moral Discourse and Cultural Politics in Early Eighteenth-Century England (Cambridge, U.K., 1994), xiii, 217p.Daniel Gordon, Citizens Without Sovereignty: Equality and Sociability in French Thought, 1670–1789 (Princeton: Princeton University Press, 1994), viii, 270p.Dena Goodman, The Republic of Letters: A Cultural History of the French Enlightenment (Ithaca and London: Cornell University Press, 1994), xiii, 338p.E. J. Hundert, The Enlightenment’s “Fable”: Bernard Mandeville and the Discovery of Society (Cambridge: Cambridge University Press, 1994), xii, 284p.The pre-modern political world was broken and remade in the two centuries that separate Montaigne from Jefferson. The long agony of the mixed constitution that began in the civil wars which raged in Iberia, France, the Low Countries, and England and seemed settled by the widespread adoption of the maxims of reason of state, revived at the end of the period, with revolution in Poland, Denmark, Sweden, Geneva, and, more famously, [End Page 725] British North America and France. The problem, classically, turned on the location of sovereignty, or supreme authority, in political systems designed to balance and diffuse rather than concentrate power. When budget deficits and fratricidal culture wars raised the cry of “necessity”—with the knowledge, of course, that necessity knew no law—estates and kings across Europe found themselves at daggers drawn. The claim that the ruler, who naturally was wholly committed to the common good, had therefore the ability to take emergency action was used both by those accustomed to rule and those newly attained to it by force. The pursuit of an “interest” that was identified with the nation’s effectively marginalized discussions of right and law while still serving an essentially constitutional, justificatory role in political debate. But if unchecked authority was necessary in order to meet the challenge of a world characterized by change and chance and thus had to reside somewhere, was there anything that made its exercise by one body more appropriate than another? This was the question that lay behind the late eighteenth-century repudiation of the reason of state “solution” to the problem of the mixed constitution. The answer, which clearly underpinned the establishment in fact of what had first been theorized already a century earlier, was that only consent could legitimate the exercise of sovereignty in time of necessity.1Representation, in one form or another, was the acknowledged solution to the problem formulated by Hobbes: “the name of Tyranny, signifieth nothing more, nor less, than the name of Sovereignty, be it in one, or many men, saving that they that use the former word are understood to be angry with them they call Tyrants.” But representation also acknowledged the reality behind the charged category of “citizenship”: most people in most places could not be said to live the life of the active citizen celebrated in Roman republican literature. Hence Hobbes’s attack on recourse to classical exempla in general, and the Libertas of Lucca in particular. The idea of civis as law-abiding subject was as radical a redrawing of the terms of debate as the identification of human nature with unsociability. Insofar as politics, classically, justified itself as the means for individual self-perfection, the practice of the ancient citizen could be conceived of as the practice of that best life speculated upon by philosophers. For the represented citizen, however, politics necessarily occupied a more subsidiary position. What, then, defined the best life to which he could aspire?There is no simple answer to this question, and the early modern ambivalence has persisted into our own time... (shrink)